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Electron microscopy Synapses were identified and selected for 3D ultrastructural analysis in tiled 11000 x magnification overviews acquired using a 200 kV Talos F200C G2 scanning/transmission electron microscope equipped with a 16 MP Ceta CMOS camera (Thermo Scientific) and MAPS v3.1 software (Thermo Scientific)

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The authors found that this COF-based Fe 2+ catalyst provided abundant active sites to locally activate a doxorubicin prodrug, while simultaneously releasing tumor-associated antigens (TAAs) and triggering ICD ( Figure 10B )

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