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P21 dosing Standard protocol: 1-2mg intramuscularly or subcutaneously daily for 2-4 weeks

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Mitochondrial aspartate deficiency disrupts the regeneration of the metabolic cofactor nicotinamide adenine dinucleotide (NAD), leading to ADP-denucleosylation of the endoplasmic reticulum (ER) sensor GRP78/BiP

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