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[2] The underlying mechanism involves the prostate pressing on the urethra thereby making it difficult to pass urine out of the bladder

This requires a basic understanding of anatomy and a clear objective

Objective inflammation assessment: Depending on the clinical situation, assessment may include blood tests, stool markers such as faecal calprotectin, imaging, colonoscopy, gastroscopy or other investigations to understand whether symptoms are linked to active inflammation or another gut condition

Even more specifically, rats studied predominantly by one research group in Zagreb, Croatia

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Checklist for adherence: baseline labs, informed consent, dosing log, adverse event log, follow-up schedule, and stop criteria