In addition, some other animal models, apart from the four mentioned, will not be discussed in this review, as they do not adequately mimic RA comorbidities (35)
Additionally, high-fat diet-induced lipid biosynthesis enzyme induction, including , , and , is more pronounced in the livers of Nrf2 / mice [76]
Additionally, the absorption process itself is competitive, with amino acids and other nutrients vying for uptake in the small intestine
Nowadays, although some HDACi including VPA, lamotrigine and SAHA [172] are approved or enrolled in clinical trials for the treatment of epilepsy, they always show some adverse effects such as hepatic injury, teratogenicity and so on, which are largely attributed to the global inhibition of HDACs for these drugs
Vitamins C and E further contribute to nutritional support and help meet daily antioxidant requirements
CNS Neurosci Ther 30:e14521