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[44] were treated with NEM after sample collection and stored until analyses

Thus, to gather additional evidence about the identity of the LDOX oxidation product, we performed enzymatic reactions in buffer containing H 2 18 O, exploiting the expected equilibrium between the gem-diol flavan-3,3,4-triol ( 4 ) and the corresponding ketone flavan-3-on-4-ol ( 7 ) (Fig

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The specificity of the alpha-2 helix stems from the assortment of amino acids in the domain that interacts with the glycine residue of glutathione