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Nordic Cochrane Center, Cochrane Collaboration, 2001)

Male smokers had more than three times the stroke risk of non-smokers, and 45- to 49-year-olds nearly five times the risk

And the principle that we came up with is to devote a certain percentage of the reviewing resources to those products that have, or are having, the greatest impact on public health, either positive or negative, simply by virtue of share of market. The other aspect Zeller said the FDA is considering is fairness, giving priority to companies that submitted applications on time, regardless of that companys size or market share

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