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In OA, fibroblast-like synoviocytes and synovial macrophages acquire a pro-inflammatory phenotype, secreting high levels of cytokines and chemokines and prostaglandins, together with matrix-degrading enzymes and nitric oxide

Moreover, it has been shown that stomach cancer is more likely to develop as a result of the oxidative stress brought on by CagA-positive bacteria (74), in which H pylori CagA produces cells with oxidative DNA damage by inducing spermine oxidase (SMO), and a portion of these cells are apoptosis-resistant and therefore highly susceptible to developing cancer (75)

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Microglia in post-mortem brain tissue of patients with bipolar disorder are not immune activated

Read a scientific review on Glutathiones role in health from the National Library of Medicine

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